Budipine Chemical formula
Synonyms: Budipino; Budipinum. 1tert-Butyl-4,4-diphenylpiperidine.
Cyrillic synonym: Будипин.

💊 Chemical information

Chemical formula: C21H27N = 293.4.
CAS — 57982-78-2.
ATC — N04BX03.
ATC Vet — QN04BX03.

💊 Profile

Budipine is a phenylpiperidine derivative used as an adjunct in the treatment of parkinsonism. It is given orally as the hydrochloride in daily doses of up to 60 mg.
1. Spieker S, et al. Tremorlytic activity of budipine: a quantitative study with long-term tremor recordings. Clin Neuropharmacol 1995; 18: 266–72
2. Groen H, et al. A study to investigate the pharmacokinetics and metabolism of budipine after administration of a single oral dose of [ C]-B757-01 to six healthy volunteers. Br J Clin Pharmacol 1999; 48: 771P–772P
3. Malsch U, et al. Monotherapie der Parkinsonschen Erkrankung mit Budipin: ein randomisierter Doppelblindvergleich mit Amantadin. Fortschr Neurol Psychiatr 2001; 69: 86–9
4. Przuntek H, et al. Budipine provides additional benefit in patients with Parkinson disease receiving a stable optimum dopaminergic drug regimen. Arch Neurol 2002; 59: 803–6.

💊 Preparations

Proprietary Preparations

Ger.: Parkinsan.
Published October 29, 2018.