Masoprocol Chemical formula
Synonyms: CHX-10; CHX-100; Masoprocolum; Mesonordihydroguaiaretic Acid; meso-NDGA. meso-4,4′-(2,3-Dimethyltetramethylene)dipyrocatechol.
Cyrillic synonym: Мазопрокол.

Chemical information

Chemical formula: C18H22O4 = 302.4.
CAS — 27686-84-6.
ATC — L01XX10.
ATC Vet — QL01XX10.


Masoprocol is a 5-lipoxygenase inhibitor isolated from the chaparral or creosote bush, Larrea tridentata. It is reported to have antineoplastic activity. It has been used in the topical treatment of actinic (solar) keratoses. Local irritation and contact dermatitis have occurred.
Published January 21, 2019.