Sulconazole Nitrate

Sulconazole Nitrate Chemical formula
Synonyms: Nitrato de sulconazol; RS-44872; RS-44872-00-10-3; Sulconazole, Nitrate de; Sulconazoli Nitras; Sulkonazol Nitrat. 1-[2,4Dichloro
Cyrillic synonym: Сульконазола Нитрат.

💊 Chemical information

Chemical formula: C18H15Cl3N2S,HNO3 = 460.8.
CAS — 61318-90-9 (sulconazole); 61318-91-0 (sulconazole nitrate).
ATC — D01AC09.
ATC Vet — QD01AC09.


In Fr. and US.

USP 31

(Sulconazole Nitrate). A white to off-white crystalline powder. Soluble 1 in 3333 of water, 1 in 100 of alcohol, 1 in 130 of acetone, 1 in 333 of chloroform, 1 in 286 of dichloromethane, 1 in 2000 of dioxan, 1 in 71 of methyl alcohol, 1 in 10 of pyridine, and 1 in 2000 of toluene. Protect from light.

💊 Adverse Effects and Precautions

Local reactions including blistering, burning, itching, and erythema have been reported after sulconazole use. For a discussion of the caution needed when using azole antifungals during pregnancy, see under Pregnancy in Precautions of Fluconazole.

💊 Antimicrobial Action

Sulconazole is an imidazole antifungal with activity against dermatophytes, Candida spp., and Malassezia furfur.

💊 Uses and Administration

Sulconazole is an imidazole antifungal used topically as the nitrate once or twice daily as a 1% cream or solution in the treatment of fungal skin infections including dermatophyte infections and pityriasis versicolor, and candidiasis.

💊 Preparations

Proprietary Preparations

Arg.: Antifungal; Minot†; Belg.: Myk-1; Fr.: Myk; Irl.: Exelderm†; Neth.: Myk-1; Turk.: Exelderm; UK: Exelderm; USA: Exelderm.
Published December 17, 2018.