Sertaconazole Nitrate

(BANM, rINNM)
Sertaconazole Nitrate Chemical formula
Synonyms: Nitrato de sertaconazol; Sertaconazole, nitrate de; Sertaconazoli nitras; Sertakonatsolinitraatti; Sertakonazol Nitrat; Sertakonazolnitrat; Sertakonazol-nitrát; Sertakonazolo nitratas; Szertakonazol-nitrát. (±)-1-{2,4-Dichloromethoxy]phenethyl}imidazole nitrate.
Cyrillic synonym: Сертаконазола Нитрат.

💊 Chemical information

Chemical formula: C20H15Cl3N2OS,HNO3 = 500.8.
CAS — 99592-32-2 (sertaconazole); 99592-39-9 (sertaconazole nitrate).
ATC — D01 AC14 .
ATC Vet — QD01AC14 .

Pharmacopoeias.

In Eur..

Ph. Eur. 6.2

(Sertaconazole Nitrate). A white or almost white powder. Practically insoluble in water; sparingly soluble in alcohol and in dichloromethane; soluble in methyl alcohol. Protect from light.

💊 Profile

Sertaconazole is an imidazole antifungal used topically as the nitrate as a 2% cream, gel, solution, or powder in the treatment of superficial candidiasis, dermatophytosis, seborrhoeic dermatitis, and pityriasis versicolor. In the treatment of vaginal candidiasis it is used as a 2% vaginal cream daily for 7 or 8 days or as a single dose of a 300-mg or 500-mg pessary. For a discussion of the caution needed when using azole antifungals during pregnancy, see under Pregnancy in Precautions of Fluconazole.

💊 Preparations

Proprietary Preparations

Arg.: Zalain†; Austria: Zalain†; Braz.: Gyno Zalain; Zalain; Chile: Tr om derm; Zalain; Cz.: Zalain†; Ger.: Mykosert; Zalain; Gr.: Fuganol†; Hong Kong: Zalain; Hung.: Zalain; Indon.: Dermofix; Ital.: Sertacream; Sertaderm; Sertadie; Sertagyn; Zalain†; Malaysia: Zalain†; Philipp.: Zalain; Port.: Dermofix; Sertopic; Rus.: Zalain (Залаин); Singapore: Zalain; Spain: Dermofix; Dermoseptic; Gine Zalain; Ginedermofix; Zalain; Thai.: Zalain; Turk.: Zalain; USA: Ertaczo; Venez.: Zalain.
Published December 15, 2018.