Oxiconazole Nitrate

(BANM, USAN, rINNM)
Oxiconazole Nitrate Chemical formula
Synonyms: Nitrato de oxiconazol; Oxiconazole, Nitrate d’; Oxiconazoli Nitras; Ro-13-8996; Ro-13-8996/001; Ro-13-8996/000 (oxiconazole); SGD-301-76; ST-813. 2′,4′-Dichloro-2-imidazol-1-ylacetophenone (Z)O-(2,4-dichlorobenzyl)oxime mononitrate.
Cyrillic synonym: Оксиконазола Нитрат.

💊 Chemical information

Chemical formula: C18H13Cl4N3O,HNO3 = 492.1.
CAS — 64211-45-6 (oxiconazole); 64211-46-7 (oxiconazole nitrate).
ATC — D01AC11; G01AF17.
ATC Vet — QD01AC11; QG01AF17.

💊 Profile

Oxiconazole is an imidazole antifungal applied topically as the nitrate as a cream, solution, or powder equivalent to oxiconazole 1% in the treatment of fungal infections of the skin. It is also given as a pessary in a single dose equivalent to 600 mg of oxiconazole in the treatment of vaginal candidiasis. Local reactions including burning and itching have been reported. Intravaginal preparations of azoles may damage latex contraceptives. For a discussion of the caution needed when using azole antifungals during pregnancy, see under Pregnancy in Precautions of Fluconazole.
1. Jegasothy BV, Pakes GE. Oxiconazole nitrate: pharmacology, efficacy, and safety of a new imidazole antifungal agent. Clin Ther 1991; 13: 126–41.

💊 Preparations

Proprietary Preparations

Arg.: Oxistat; Austria: Gyno-Liderman; Liderman; Oceral; Braz.: Micotin; Oceral; Oxipelle; Oxitrat†; Canad.: Oxizole†; Cz.: Gyno-Myfungar†; Myfungar; Fr.: Fonx; Ger.: Myfungar; Oceral GB†; Mex.: Gyno-Myfungar†; Myfungar; Oxistat; Rus.: Myfungar (Мифунгар); Spain: Salongo; Switz.: Oceral; Turk.: Oceral; USA: Oxistat. Multi-ingredient: India: Zoderm.
Published December 08, 2018.