Naftifine Hydrochloride

(BANM, USAN, rINNM)
Naftifine Hydrochloride Chemical formula
Synonyms: AW-105-843; Hidrocloruro de naftifina; Naftifin Hidroklorür; Naftifine, Chlorhydrate de; Naftifini Hydrochloridum; Naftifungin Hydrochloride; SN105-843 (naftifine). (E)N-CinnamylN-methyl(1-naphthylmethyl)amine hydrochloride.
Cyrillic synonym: Нафтифина Гидрохлорид.

💊 Chemical information

Chemical formula: C21H21N,HCl = 323.9.
CAS — 65472-88-0 (naftifine); 65473-14-5 (naftifine hydrochloride).
ATC — D01AE22.
ATC Vet — QD01AE22.

Pharmacopoeias.

In US.

USP 31

(Naftifine Hydrochloride). Store in airtight containers.

💊 Profile

Naftifine hydrochloride is an allylamine derivative which is fungicidal against dermatophytes, but only fungistatic against Candida spp. Naftifine hydrochloride 1% is applied topically once or twice daily for fungal skin infections, particularly dermatophytosis. Local reactions such as burning or stinging may occur.
1. Gupta AK, et al. Naftifine: a review. J Cutan Med Surg 2008; 12: 51–8.

💊 Preparations

USP 31: Naftifine Hydrochloride Cream; Naftifine Hydrochloride Gel.

Proprietary Preparations

Austria: Benecut; Exoderil; Canad.: Naftin; Cz.: Exoderil; Ger.: Exoderil; Hong Kong: Exoderil; Hung.: Exoderil; Indon.: Exoderil; Israel: Exoderil; Ital.: Suadian; Malaysia: Exoderil; Pol.: Exoderil; Rus.: Exoderil (Экзодерил); Singapore: Exoderil†; Spain: Micosona; Turk.: Exoderil; USA: Naftin.
Published December 04, 2018.