Troleandomycin

(BAN, USAN, rINN)
Troleandomycin Chemical formula
Synonyms: NSC-108166; Triacetyloleandomycin; Troleandomicina; Troleandomisin; Troléandomycine; Troleandomycinum; Troleandomysiini. The triacetyl ester of oleandomycin .
Cyrillic synonym: Тролеандомицин.

💊 Chemical information

Chemical formula: C41H67NO15 = 814.0.
CAS — 2751-09-9.
ATC — J01FA08.
ATC Vet — QJ01FA08.

Pharmacopoeias.

In Fr. and US.

USP 31

(Troleandomycin). A white, odourless, crystalline powder. It contains the equivalent of not less than 750 micrograms of oleandomycin per mg. Slightly soluble in water and in ether; freely soluble in alcohol; soluble in chloroform. A 10% solution in alcohol and water (1:1) has a pH of 7.0 to 8.5. Store in airtight containers.

💊 Profile

Troleandomycin is a prodrug of the macrolide antibacterial oleandomycin that has actions similar to those of erythromycin. It has been given orally in the treatment of susceptible infections although more effective antibacterials are generally preferred.

💊 Preparations

USP 31: Troleandomycin Capsules.

Proprietary Preparations

Ital.: Triocetin†; Turk.: Te k m i s i n ; USA: TAO†.
Published May 08, 2019.