Sulfaguanidine

(BAN, rINN)
Sulfaguanidine Chemical formula
Synonyms: Solfaguanidina; Sulfaguanidiini; Sulfaguanidin; Sulfaguanidina; Sulfaguanidinas; Sulfaguanidinum; Sulfaguanidyna; Sulfamidinum; Sulginum; Sulphaguanidine; Szulfaguanidin. 1-Sulphanilylguanidine; N′Amidinosulphanilamide.
Cyrillic synonym: Сульфагуанидин.

💊 Chemical information

Chemical formula: C7H10N4O2S = 214.2.
CAS — 57-67-0 (anhydrous sulfaguanidine); 6190-55-2 ATC — A07AB03.
ATC Vet — QA07AB03.

Pharmacopoeias.

In Eur.. Viet. includes the monohydrate.

Ph. Eur. 6.2

(Sulfaguanidine). A white or almost white, fine crystalline powder. Very slightly soluble in water and in alcohol; slightly soluble in acetone; practically insoluble in dichloromethane. It dissolves in dilute solutions of mineral acids. Protect from light.

💊 Profile

Sulfaguanidine is a sulfonamide with properties similar to those of sulfamethoxazole. It is absorbed to a limited extent from the gastrointestinal tract and may therefore be more likely to cause systemic effects than less well absorbed drugs such as phthalylsulfathiazole and succinylsulfathiazole. It is used, usually with other drugs, in the treatment of gastrointestinal infections, and has also been applied locally to the skin and throat.

💊 Preparations

Proprietary Preparations

Fr.: Enteropathyl. Multi-ingredient: Braz.: Sanadiar†; Chile: Carbon Sulfaguanidina; Mex.: Neopecsul; Thai.: Biodan†.
Published May 08, 2019.