Sitafloxacin

(USAN, rINN)
Sitafloxacin Chemical formula
Synonyms: DU-6859 (anhydrous sitafloxacin); DU-6859a (sitafloxacin sesquihydrate); Sitafloxacine; Sitafloxacino; Sitafloxacinum. (−)-7[(7S)-7-Amino-5-azaspiro[2.4]hept-5-yl]-8-chloro-6-fluoro-1[(1R,2S)-2-fluorocyclopropyl]-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid.
Cyrillic synonym: Ситафлоксацин.

💊 Chemical information

Chemical formula: C19H18ClF2N3O3 = 409.8.
CAS — 127254-12-0 (anhydrous sitafloxacin); 16325337-0 (sitafloxacin monohydrate); 163253-35-8 (sitafloxacin sesquihydrate).
NOTE. Sitafloxacin exists in several hydration states; the name sitafloxacin has been used to refer to both the anhydrous substance and the sesquihydrate (C 19 H 18 ClF 2 N 3 O 3 ,1 ⁄ H 2 O = 436.8); the latter is known in Japan as sitafloxacin hydrate.

💊 Profile

Sitafloxacin is a fluoroquinolone that is given orally in the treatment of susceptible infections.

💊 Preparations

Proprietary Preparations

Jpn: Gracevit.
Published May 08, 2019.