Isepamicin Sulfate

Synonyms: Isepamicin Sulphate (BANM); Isépamicine, Sulfate d’; Isepamicini Sulfas; Isepamisin Sülfat; Sulfato de isepamicina.
Cyrillic synonym: Изепамицина Сульфат.

💊 Chemical information

Chemical formula: C22H43N5O12,2H2SO4 = 765.8.
CAS — 68000-78-2.
ATC — J01GB11.
ATC Vet — QJ0 1GB11.


In Jpn, which specifies a variable amount of H 2 SO 4 .

💊 Profile

Isepamicin is a semisynthetic aminoglycoside with actions and uses similar to those of gentamicin. It is reported not to be degraded by many of the enzymes responsible for aminoglycoside resistance. Isepamicin sulfate is given by intramuscular injection or intravenous infusion in a dose of up to 15 mg/kg daily in 2 divided doses. Once-daily dosage may be possible in selected patients. Dosage should be adjusted based on serumisepamicin concentration monitoring. In adults, the total daily dose should not exceed 1.5 g.
1. Tod M, et al. Clinical pharmacokinetics and pharmacodynamics of isepamicin. Clin Pharmacokinet 2000; 38: 205–23.

💊 Preparations

Proprietary Preparations

Austria: Isepacin†; Belg.: Isepacine†; Cz.: Isepacin†; Fr.: Isepalline†; Ital.: Isepacin†; Mex.: Isepacin†; Turk.: Isepacine.
Published March 29, 2019.