Cefozopran Hydrochloride

(rINNM)
Cefozopran Hydrochloride Chemical formula
Synonyms: Céfozopran, Chlorhydrate de; Cefozoprani Hydrochloridum; Hidrocloruro de cefozoprán. (−)-1-{[(6R,7R)-7-[2-(5-Amino1,2,4-thiadiazol-3-yl)glyoxylamido]-2-carboxy-8-oxo-5-thia-1azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-1H-imidazo[1,2b]pyridazin-4-ium hydroxide inner salt, 7 2 -(Z)-(O-methyloxime), hydrochloride.
Cyrillic synonym: Цефозопрана Гидрохлорид.

💊 Chemical information

Chemical formula: C19H17N9O5S2,HCl = 552.0.
CAS — 113359-04-9 (cefozopran); 113981-44-5 (cefozopran hydrochloride).

Pharmacopoeias.

In Jpn.

💊 Profile

Cefozopran is a cephalosporin antibacterial used parenterally as the hydrochloride.
1. Iwahi T, et al. In vitro and in vivo activities of SCE-2787, a new parenteral cephalosporin with a broad antibacterial spectrum. Antimicrob Agents Chemother 1992; 36: 1358–66
2. Paulfeuerborn W, et al. Comparative pharmacokinetics and serum bactericidal activities of SCE-2787 and ceftazidime. Antimicrob Agents Chemother 1993; 37: 1835–41
3. Fujii R, et al. Pharmacokinetics and clinical effects of cefozopran in pediatric patients. Jpn J Antibiot 1996; 49: 17–33.

💊 Preparations

Proprietary Preparations

Jpn: Firstcin.
Published January 09, 2019.