Cefetamet Pivoxil Hydrochloride

(rINNM)
Synonyms: Céfétamet Pivoxil, Chlorhydrate de; Cefetameti Pivoxili Hydrochloridum; Cefetametpivoxilhydroklorid; Cefetametum Pivoxili Hydrochloridum; Hidrocloruro de cefetamet pivoxilo; Kefetameettipivoksiilihydrokloridi; Ro-15-8075 (cefetamet pivoxil). Cefetamet pivaloyloxymethyl hydrochloride.
Cyrillic synonym: Цефетамета Пивоксила Гидрохлорид.

💊 Chemical information

Chemical formula: C20H25N5O7S2,HCl = 548.0.
CAS — 65243-33-6 (cefetamet pivoxil); 111696-23-2 (cefetamet pivoxil hydrochloride). ATC — J01DD10.
ATC Vet — QJ01DD10.

💊 Profile

Cefetamet is a third-generation cephalosporin antibacterial similar to cefixime (below). It has been given orally as the hydrochloride of the pivaloyloxymethyl ester, cefetamet pivoxil hydrochloride, which is hydrolysed to cefetamet in vivo. The usual dose is 500 mg twice daily. For reference to carnitine deficiency occurring with some pivaloyloxymethyl esters, see Pivampicillin.
1. Bryson HM, Brogden RN. Cefetamet pivoxil: a review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs 1993; 45: 589–621
2. Blouin RA, Stoeckel K. Cefetamet pivoxil clinical pharmacokinetics. Clin Pharmacokinet 1993; 25: 172–88.

💊 Preparations

Proprietary Preparations

Braz.: Globocef†; Ger.: Globocef†; Hong Kong: Globocef†; Ital.: Globocef†; Pol.: Tar ce v i s† ; Port.: Cefec†; Globocef†; Switz.: Globocef†.
Published December 30, 2018.