Carindacillin Sodium

Carindacillin Sodium Chemical formula
Synonyms: Carbenicillin Indanyl Sodium (USAN); Carindacilina sódica; Carindacilline Sodique; CP-15464-2; Natrii Carindacillinum. Sodium (6R)-6-[2-(indan-5-yloxycarbonyl)-2-phenylacetamido]penicillanate.
Cyrillic synonym: Натрий Кариндациллин.

💊 Chemical information

Chemical formula: C26H25N2NaO6S = 516.5.
CAS — 35531-88-5 (carindacillin); 26605-69-6 (carindacillin sodium).
ATC — J01C A05.
ATC Vet — QJ01CA05.


In US.

USP 31

(Carbenicillin Indanyl Sodium). A white to off-white powder. Soluble in water and in alcohol. pH of a 10% solution in water is between 5.0 and 8.0. Store in airtight containers.

💊 Profile

Carindacillin is the indanyl ester of carbenicillin to which it is hydrolysed after absorption from the gastrointestinal tract. Its use is restricted to the treatment of urinary-tract infections due to Pseudomonas spp. and other sensitive bacteria including Proteus spp. Carindacillin is given orally as the sodium salt; 535 mg of carindacillin sodium is equivalent to about 382 mg of carbenicillin. Usual doses, expressed in terms of carbenicillin, are 382 to 764 mg four times daily.

Sodium content.

Each g of carindacillin sodium contains about 1.9 mmol of sodium.

💊 Preparations

USP 31: Carbenicillin Indanyl Sodium Tablets.

Proprietary Preparations

USA: Geocillin†.
Published December 12, 2018.