Synonyms: Carbenicillin Indanyl Sodium (USAN); Carindacilina sódica; Carindacilline Sodique; CP-15464-2; Natrii Carindacillinum. Sodium (6R)-6-[2-(indan-5-yloxycarbonyl)-2-phenylacetamido]penicillanate.
Cyrillic synonym: Натрий Кариндациллин.
💊 Chemical information
Chemical formula: C26H25N2NaO6S = 516.5.
CAS — 35531-88-5 (carindacillin); 26605-69-6 (carindacillin sodium).
ATC — J01C A05.
ATC Vet — QJ01CA05.
USP 31(Carbenicillin Indanyl Sodium). A white to off-white powder. Soluble in water and in alcohol. pH of a 10% solution in water is between 5.0 and 8.0. Store in airtight containers.
Carindacillin is the indanyl ester of carbenicillin to which it is hydrolysed after absorption from the gastrointestinal tract. Its use is restricted to the treatment of urinary-tract infections due to Pseudomonas spp. and other sensitive bacteria including Proteus spp. Carindacillin is given orally as the sodium salt; 535 mg of carindacillin sodium is equivalent to about 382 mg of carbenicillin. Usual doses, expressed in terms of carbenicillin, are 382 to 764 mg four times daily.
Sodium content.Each g of carindacillin sodium contains about 1.9 mmol of sodium.
USP 31: Carbenicillin Indanyl Sodium Tablets.
Proprietary PreparationsUSA: Geocillin†.
Published December 12, 2018.