Benzathine Phenoxymethylpenicillin

(USAN)
Benzathine Phenoxymethylpenicillin Chemical formula

💊 Chemical information

Benzatin Fenoksimetil Penisilin; Benzatina fenoximetilpenicilina; Penicillin V Benzathine laethylendiaminum. N,N′-Dibenzylethylenediammonium bis[(6R)6-(2-phenoxyacetamido)penicillanate].
Chemical formula: (C16H18N2O5S)2,C16H20N2 = 941.1.
CAS — 5928-84-7 (anhydrous benzathine phenoxymethylpenicillin); 63690-57-3 (benzathine phenoxymethylpenicillin tetrahydrate).
ATC — J01CE10.
ATC Vet — QJ01CE10.

Pharmacopoeias.

In US.

USP 31

(Penicillin V Benzathine). A practically white powder having a characteristic odour. Soluble 1 in 3200 of water, 1 in 330 of alcohol, 1 in 37 of acetone, 1 in 42 of chloroform, and 1 in 910 of ether. pH of a 3% suspension in water is between 4.0 and 6.5. Store in airtight containers.

💊 Profile

Benzathine phenoxymethylpenicillin has actions and uses similar to those of phenoxymethylpenicillin and is given orally in the treatment of susceptible mild to moderate infections. Doses are expressed in terms of phenoxymethylpenicillin.

💊 Preparations

USP 31: Penicillin V Benzathine Oral Suspension.

Proprietary Preparations

Austral.: Abbocillin-V; Cilicaine V; Austria: Ospen; Canad.: Pen-Vee†; Cz.: Ospen; Fr.: Oracilline; Ger.: InfectoBicillin; Gr.: Ospen; Hung.: Ospen; Oxybion†; Pol.: Ospen; Rus.: Ospen (Оспен); Spain: Benoral; Switz.: Ospen; Phenocillin; Turk.: Pen-Os; Venez.: Ospen.
Published December 01, 2018.